Friday, November 30, 2012

Aspirin link, in order to reduce the risk of liver cancer

The new study found that aspirin and other nonsteroidal anti-inflammatory drugs or non-steroidal anti-inflammatory drugs may help prevent serious liver disease, including cancer.

Aspirin users were 41 percent less likely to develop liver cancer, 45 percent less likely to die from chronic liver disease than non-users, according to the study of Vikrant Sahasrabuddhe, Rockville, Maryland, USA, United States National Cancer Research by and his colleagues.

Also lower the risk of death from chronic liver disease and other non-steroidal anti-inflammatory drugs, but less with liver cancer, the study of more than 300,000 middle-aged and older people.

"These associations highlight the use of aspirin, if confirmed, may open up new prospects for the chemoprevention of liver cancer and chronic liver disease wrote," in the magazine published by the U.S. National Cancer Institute on December 5.

The results showed that in colorectal cancer and other cancer types, past performance is not surprising, oncologist at the University of Alabama at Birmingham, Dr. Boris Pasche, MedPage Today in an interview with reporters, said .

"We are seeing more and more evidence that long-term use of aspirin can prevent the crowd of several types of NSAID use in the prevention of cardiovascular events in cancer development, he said.

However, in addition to myocardial protection is a possible additional benefits that aspirin may be necessary and beneficial to the protection of the liver, according to other experts.

For one thing, it has been a good strategy, do not increase the risk of bleeding in the way of non-steroidal anti-inflammatory drugs, Dr. Isra Levy and Carolyn Pim, University in Ontario, Ottawa, Ottawa Public Health, in pointed out in an editorial.

"In practice," they wrote, "We know and understand the reasons, in most cases, chronic liver disease and primary liver cancer virus infection, hepatitis B virus (HBV) and hepatitis C virus (HCV ), and alcohol. inexpensive, easy to use interventions to prevent most of these diseases. "

In addition, the risk of developing liver cancer is low enough chemoprevention in the general population is no sense to weigh the risk of bleeding, Dr. Marian said liver disease yellow at Henry Ford Hospital in Detroit.

Higher risk populations, for whom, prevention strategies need - cirrhosis - may not be a good candidate, because they are at a higher risk of bleeding, Huang told MedPage Today in an interview with reporters.

U.S. National Institutes of Health, the findings of the American Association of Retired Persons may be good enough prospective study to see whether the benefits outweigh the risks, the population, "Pasche recommendations.

A combination of diet and health study included 300,504 adults aged 50-71 years enrollment report their NSAID use baseline questionnaire.

Queue from six states (California, Florida, Louisiana, New Jersey, North Carolina and Pennsylvania) and two metropolitan areas (Atlanta and Detroit). Respondents, 73% of the respondents use aspirin, 56% of people use other non-steroidal anti-inflammatory drugs.

Aspirin effect is independent of the frequency of use.

All results were adjusted for age, gender, race or ethnicity, body mass index, smoking, alcohol consumption and diabetes.

The researchers suggested that the queue NSAID use anti-inflammatory or other mechanisms may be due to the obvious advantages.

However, they admit that the lack of a dose response found only monthly non-aspirin NSAID use "display the results should be interpreted with considerable caution, because they may also reflect unmeasured confounders.

IARC Texas $ 110,000 grant to bypass the panel of judges

National Cancer Institute confirmed, approved a grant of $ 11 million, in 2010 - the largest amount of money granted - not scientific or commercial reviews.

In cancer prevention and the Texas Institute of disclosure after a tumultuous summer, it has revoked a $ 20 million grant to a group led by the University of Texas MD Anderson Cancer Center, because the integrity of the review process.

Awarded in 2010, recruitment, migration and the formation of the biotechnology company, headquartered in Dallas, riders treatment. "Riders to the discovery and development of new anti-cancer drugs. Grant the grant of the first four commercial organizations.

Cancer Institute, the internal audit found that its main business personnel when Jerry Cobbs, incorrect riders commercialization awards Oversight Committee recommended list. Although it is not commercial or scientific review panel reviewed riders granted approval.

Cobbs month resignation undisclosed reasons. He was unable to comment on the matter Thursday.

"CPRIT must have the trust of our fellow Texans, we not only do a great job, but we also do everything the right way," Bill Gimson, executive director, said in a statement released on Thursday night.

Recalling skip

Although the argument seems to blame Cabos, said the agency's Web site, which is the executive director of Gimson work submitted to the Oversight Committee ultimately approved list of applications granted share options. It says the commercialization of the Vetting Committee recommendations, the executive director.

The officials refused to disclose how many grants have been distributed to a large force. The founder of the company, the University of Texas Southwestern biochemist 史蒂芬麦克 Knight did not respond to requests for comment.

Large forces press conference, announced the grant in July 2010, Cobbs was quoted as saying the relationship between The award marks the national institutions and companies is just the beginning.

: "CPRIT very pleased to provide significant value in the development of breakthrough cancer treatment, cancer patients and their families, and their potential to contribute to the success of" Cobbs said. "We anticipate a long and fruitful relationship."

The agency said that the riders have been re-submitted its recommendations to the commercialization and scientific review.

Voters approved the establishment of the cancer initiative $ three hundred million taxpayer-funded bonds issued in 2007, State agencies and enterprises to 10 years of cancer research and treatment. It's the first grant was awarded in late 2009.

Collective resignation

Summer and autumn institutions, to meet the scientific review led by the Nobel laureate in economics, aluminum Gilman resign. Scientists cry foul over 20 million U.S. dollars in grants awarded to Dr researcher at the University of Texas MD Anderson Cancer Center is a research team led by Dr. Ronald DePinho, president of the agency's wife Linda Exhibition anticancer drugs commercialization.

Resignation scientists cited concern about the cancer initiative of some members of the political appointees of the Oversight Committee, especially biotechnology Houston investor Charles Tate, use undue influence to ensure that certain business grant funds, rather than a scientific review.

Tate is still a member of the oversight committee of the institution.

The cancer organizations the MD Anderson granted controversy, has vowed to reform the process through business subsidies gold. Also hired a compliance officer the Patricia Vojack, add another layer of oversight.

Its actions are expected to review and the National Audit Office will make recommendations to the Legislative Council in 2013, the relevant agencies in January.

Prior to this, the the latest whistleblowers State governor Rick Perry said, support for CPRIT, said in October, the chairman of the board, the telecommunications company manager James Mansour, has done a "special".

Criticism expressed

External observers have been charitable, however. Influential scientific journal "Nature" called for the resignation, due to the the CPRIT obvious "cronyism" Mansour.

And an independent ethicists, said Paul Wolpe of Emory University, which is hard to imagine that the body can maintain its credibility unless Mansour and other leaders to step down. "I see here is damage control, rather than responsibility, deafness, rather than sensitivity," Volpe said in October.

Wisconsin cancer support group drew the name comedian Gilda Radner decline criticism

The young generation may not be able to identify a character driven by comedian Gilda Radner. They also recall that the U.S. National Cancer support group Ladner original cast member of Saturday Night Live, "died 23 years ago, they named.

Gilda club in trouble, the club decided to change its name, in part because it is worried that a lot of people do not know is who Radnor Madison area chapter. But sparked anger some fans Ladner _ who see it as a slight woman of dignity and humor _ the face of cancer, and lead to other chapters across the country, and hurried reiterated absolutely no intention of changing their names.

Club executive director Stenz Madison area, sirens Lannia said her organization decided to change its name, you realize that most college students, Ladner, born in died in 1989, the Cancer Support Community Southwest Wisconsin.

"We see young people and young adults, cancer diagnosis and treatment, Stenz told the Wisconsin State Journal," We want to make sure we are very clear that they do not have too much confusion, cause people do not come to our door. '

Her tone angered some fans of Radnor, releasing a storm of criticism, the organization's Facebook page.

To write markup Bo education you do to teach my children, when they died of cancer, and their names will be erased from the history of the past 20 years, because the next generation does not know who they are. Way, so they hope! Klein, in Arlington, Texas, the 44-year-old full-time college students.

He told AP reporters De Ji and Chu Hu Los Angeles Dana name is an insult to her memory.

Stenz Linda F, the problem of the AP, National Group executive vice president. House said there is no evidence that the aspirations of young people are not familiar with the organization's mission to clear Ladner and name change. She called Stenz opinion "is not accurate."

Gilda Radner fibrous tissue is a very important part, "House said," never intended, and has no intention of losing Gilda as part of the organization. '

The Stenz Association on Thursday held a ceremony to commemorate the name change, which will be phased in over the next month.

Ladner, in 1986, was diagnosed with ovarian cancer, to seek support in the health community in California, and wrote about her experiences in her book, which is a new thing, "catch her individuality phrase 1.

Gilda Club on the East Coast in 1991, to commemorate her legacy of her friends and family. The name was inspired by Ladner said: "After her cancer diagnosis, I would prefer not to belong to a member of the elite club of my stuff."

Gilda Club global health community in 2009, mergers, joint headquarters in Washington, changed its name to the Cancer Support Community. Local chapters to keep their own name, or to switch to the selected cancer support community, Lou said.

She said, in 56 chapters around the world to provide free medical care for 40 million U.S. dollars per year, about 10,000 cancer patients and their families. 20 In these chapters, Gilda Club, known as the Healthy Communities, 23 cancer support community.

Change the name of the chapter is meaningful Beloit College Professor Ron · Nief, different generations career in southern Wisconsin is a different way to learn how to look at the world. He said Gilda club, which may become more difficult to attract donations, because almost no one remembers saw on television Ladner.

"I think we all want to keep our traditions alive," he said, "but in this case, which is the representative of the Group, as well as how we raise funds, and will never become a reality."

Radner's husband, actor Gene Wilder, said he did not like the name change, but his understanding. He said that if he wanted to break the news to his late wife, she might ask, "They took me out of here?"

"I said," do not throw you, my dear, to get more money. "She said, 'OK, I think, if they have, they have," he said, "That's too bad, I hope not, but I understand."

Ladner's health center in the Los Angeles support group updated its name. Julia, now known as "Cancer Support Community Benjamin Center's director of marketing, said the sick people who Google the word cancer, but it helps to name the word.

Gilda Club's name other organizations related to the maintenance company. Run a branch in Chicago, LauraJane Hyde, said her team has spent 15 years teaching Ladner's name is synonymous with cancer support, the same reason people know Starbucks to sell, even if the "coffee" is not a person in its names.

"A lot of people think the name is very warm," she said. He said: "The donations we will lose if we change it."

Ladner club is still a strong presence in the Madison area, even in her name Middleton in the suburbs. Ladner line of wall paintings and sketches. A description of her in the top of the State Council building in Madison. Another imagine her sitting on the coast of Mendota, the lake University of Wisconsin - Madison.

Conference room named after her Saturday Night Live characters, including the New York street smarts reporter, Roseanne Roseannadana synchronization edit Miss Emily Litella voice impede the Baba doll talk show host Barbara Walters stupid things.